Resources
Resources:
The Edward R. and Anne G. Lefler Fellows
| Fellow (Sponsor) | Project Title | Award Dates | Institution / Department |
|---|---|---|---|
| Prada, Claudia (Frosch) | Regulation of progression of cerebral amyloid angiopathy | 07/01/07-6/30/08 | |
| Tofaris, George (Goldberg) | Proteasome function in neurodegenerative diseases | 07/01/07-6/30/08 | |
| Fitzgerald, Jamie (Assad) | Probing cortical plasticity mechanisms | 07/01/07-6/30/08 | |
| Myre, Michael (W Wasco) | A novel small molecule induces cell cycle arrest and decreases processing of the amyloid_precursor protein | 07/01/07-6/30/08 | |
| Narayanan, S (M Wolfe) | Toward a structural insight into the catalytic mechanism of intramembrane proteolysis | 07/01/07-6/30/08 | |
| Myre, Michael (W Wasco) | A novel small molecule induces cell cycle arrest and decreases processing of the amyloid_precursor protein | 07/01/06-6/30/07 | |
| Narayanan, S (M Wolfe) | Toward a structural insight into catalytic mechanism of intramembrane proteolysis | 07/01/06-6/30/07 | |
| Periquet, Magali (M. Feany) | α-Synuclein toxicity and aggregation in a Drosophila model of Parkinson's Disease | 07/01/06-6/30/07 | |
| Sardi, Sergio Pablo (G Corfas) | γ-Secretase-dependent erbB4 regulation of neuronal precursor fate | 07/01/06-6/30/07 | |
| Sohur, U. Shivraj (J Macklis) | Molecular development of corticostriatal projection neurons: toward neuronal support and circuit repair in neurodegenerative diseases | 07/01/06-6/30/07 | |
| Periquet, Magali (M. Feany) | α-Synuclein toxicity and aggregation in a Drosophila model of Parkinson's Disease | 07/01/05-6/30/06 | |
| Sardi, Sergio Pablo (G Corfas) | γ-Secretase-dependent erbB4 regulation of neuronal precursor fate | 07/01/05-6/30/06 | |
| Sohur, U. Shivraj (J Macklis) | Molecular development of corticostriatal projection neurons: toward neuronal support and circuit repair in neurodegenerative diseases | 07/01/05-6/30/06 | |
| Fradinger, Erica A (D. Teplow) | Biological activity of soluble Aß oligomers and their link to Alzheimer's disease | 7/1/04-6/30/05 | BWH- Neurology |
| Kondo, Masahiro (D. Schmucker) | Functional significance of the molecular diversity of the Down Syndrome Cell Adhesion Molecule | 7/1/04-6/30/05 | DFCI- Neurobiology |
| Robles, Maria S. (C. Weitz) | Proteomic analysis of the mammalian circadian clock | 7/1/04-6/30/05 | HMS- Neurobiology |
| Yuan, Zengqiang (A. Bonni) | Cdh1-APC regulation of axonal growth | 7/1/04-6/30/05 | HMS- Pathology |
| Chyung, Jay Hwan (D. Selkoe) | Cell surface events in the processing of APP to generate Aß | 7/1/03-6/30/04 | MGH- Medicine |
| Kornilova, Anna Y (M. Wolfe) | Probing_-secretase with photoactivable inhibitors | 7/1/03-6/30/04 | BWH- Neurology |
| Padoa-Schioppa, Camillo (J. Assad) | Neural correlates of choice in the orbitofrontal cortex | 7/1/03-6/30/04 | HMS- Neurobiology |
| Isaacs, Adrian (B. Yankner) | The role of mitochondrial dysfunction in Alzheimer's disease and brain aging | 7/1/02-6/30/03 | Children's Hospital- Neurology |
| Kim, Taekyung (M. Greenberg) | Calcium signaling to the nucleus by L-type calcium channel | 7/1/02-6/30/03 |
Children's Hospital- Neurology |
| Sivasankaran, Rajeev (Z He) | Molecular mechanisms underlying myelin inhibition of axonal outgrowth | 7/1/02-6/30/03 | Children's Hospital- Neurology |
| Kirkitadze, Marina, (D. Teplow) | Conformational dynamics of amyloid B-protein fibrillogenesis | 7/1/01-6/30/02 | BWH - Neurology |
| Nieto, Marta, (C. Walsh) | Analysis of the role of homeodomain transcription factors CDP/CUX1, 2 in cortical laminar specification and axonal connectivity | 7/1/01-6/30/02 | BIDMS/HIM - Neurology |
| St. Pierre, Susan (S. Thor) | Isolation of rotund and characterization of its role in neural development | 7/1/01-6/30/02 | HMS - Neurobiology |
| O'Neill, Gilmore, Ph.D. (R. Brown) |
nvestigations of factors influencing the neurodegenerative phenotype of adrenomyeloneuropathy. | 7/1/00-6/30/01 | MGH - Neurology |
| Tannoch, Vivien, Ph.D.(L. Tsai) | Neuronal Cell Death: Impact of p25/ cyclin-dependent kinase5 activity. | 7/1/00-6/30/01 | HMS - Pathology |
| Lin, Yingxi, Ph.D. (X. He) |
The mechanism of semaphorin signaling in vertebrae axon guidance. | 7/1/00-6/30/01 | HMS - BCMP |
| Magavi, Sanjay (J. Macklis) |
Induction of neocorticalneurogenseis in the adult. | 7/1/00-6/30/01 | Children's Hospital - Neuroscience |
| Toth, Louis, Ph.D. (J. Assad) |
Sensory and volitional aspects of basal ganglia function. | 11/1/99-10/31/01 | HMS - Neurobiology |
| Beaudet, Matthew, Ph.D. (C. Saper) |
Sensory and volitional aspects of basal ganglia function. | 11/1/99-10/31/01 | HMS - Neurobiology |
| Beaudet, Matthew, Ph.D. (C. Saper) |
A gene-transfer strategy for producing an animal model of Alzheimer-like neurodegeneration. | 9/1/99-8/31/00 | Univ. of VT College of Medicine - Anatomy & Neurobiology |
| Cowan, Christopher, Ph.D. (M. Greenberg) |
Analysis of a novel FKHRL1-mediated apoptosis pathway in neurons. | 8/1/99-7/31/00 | Children's Hospital - Neuroscience |
| Schlossmacher, Michael, Ph.D. (D. Selkoe & K. Kosik) |
Cell biology of alpha-synuclein in Parkinson's disease | 7/1/99-6/30/00 | BWH - Center for Neurologic Diseases |
| Fricker, Rosemary, M.D. (J. Macklis) |
The manipulation of cortical precursor cells to replace degenerating neocortical neurons and establish connectivity with the host brain. | 7/1/98-6/30/99 | Children's Hospital - Neuroscience |
| Richardson, Jennelle, Ph.D. (K. Buckley) |
Mechanisms of prostanoid release from neurons. | 7/1/98-6/30/99 | HMS - Neurobiology |
| Rook, Martha, Ph.D. (K. Kosik) |
Translocation of specific mRNA species in neurons: visualization via a GFP linkage. | 7/1/98-6/30/99 | BWH - Center for Neurologic Diseases |
| Rosas, H. Diana, M.D. (A. Young & V. Caviness) |
Huntington's Disease: Morphometry, chemistry & cognition. | 7/1/98-6/30/99 | MGH - Neurology |
| Watson, Fiona, M.D. (R. Segal) | Retrograde signalling by neurotrophins. | 1/1/97-12/31/97 |
Beth Israel Deaconess- Neurology |
| Aboody-Guterman, Karen, Ph.D. (X. Breakefield) |
Interaction of apoE protein Alzheimer beta-amyloid protein. | 1/1/97-12/31/97 | MGH - Neurology |
| Li, Jinhe, Ph.D. (H. Potter) |
Expression, structure, and function of the presenilins. | 11/1/96-10/31/97 | HMS- Neurobiology |
| Wilson, David, Ph.D.(C. Saper) | Induction of Tau Pathology in Cultured Cells | 9/16/96-9/15/97 | Beth Israel Deaconess- Neurology |
| Orlando, Lianna (A. Young) |
Metabotrophic glutamate receptors modulate striatal excitotoxicity. | 7/1/96-6/30/97 |
MGH - Neurology |
| Sun, Yi, Ph.D. (M. Greenberg) |
Identification of the signaling cascade involved in neuronal apoptosis induced by NGF deprivation. | 2/1/96-1/31/97 | Children's Hospital - Neuroscience |
| Nadeau, Philip, Ph.D. (B. Yanker) | Studies of the pathogenic mechanism of Apolipoprotein E in human neuronal model. | 1/1/96-6/30/00 | Children's Hospital - Neuroscience |
| Watson, Deborah (D. Selkoe) |
Cerebral vascular hemorrhage caused by an Alzheimer's related mutation. | 11/1/95-10/31/96 | Children's Hospital - Neuroscience |